The crash occurred shortly after 3 p.m. between Pontaluna and Sternberg roads in Norton Shores, on the northbound lanes of the highway.
Traffic in the southbound lanes was moving slowly past the emergency vehicles, some of which were parked along the southbound median wall.
Northbound traffic was backed up to Ridge Street in Ferrysburg. Cars taking the VanWagoner Road exit were also backed up down the highway.
More information will be provided as it becomes available.